This month’s journal-based CME article is titled "Yttrium-90 trans-arterial radioembolization for chemotherapy- refractory intrahepatic cholangiocarcinoma: a prospective, observational study."

There is limited data on locoregional therapies for ICC, especially those offered second-line after chemo-resistance. Given that ICC has few treatment options and has poor survival, identifying the role of TARE in this population is critical to advance the field and our knowledge. This study provides the readers with greater insight into the role of TARE for chemorefractory ICC and provides data on expected overall survival, progression of disease and the incidence of TARE-related complications.

This program is designed to meet the educational needs of interventional radiologists, medical oncologists, radiation oncologists, hepatobiliary and transplant surgeons, nurses, techs, and trainees at all levels with special interest in oncology.

To receive CME credit for this journal-based CME activity, participants must read the journal article and score 75% or better on the post test. Participants will have three opportunities to score 75% or better.

Learning Objectives
After participating in this journal-based CME activity, learners should be able to:

• Describe the expected overall survival after TARE for chemotherapy-refractory ICC
• Cite the median progression-free survival after TARE for chemotherapy-refractory ICC
• List the incidence of TARE related complications in this cohort of patients

Authors
JVIR CME Editor
Nishita Kothary, MD
Stanford University Medical Center, Stanford CA

Authors

Judith White
Grace Carolan-Rees
Megan Dale
Hannah E Patrick
Teik C See
Jon K Bell
Derek M Manas
Adrian Crellin
Nicholas J Slevin
Ricky A Sharma, MA FRCP FRCR PhD

Cedar, Cardiff & Vale University Health Board, Cardiff Medicentre, Heath Park, Cardiff
Cedar, Cardiff University Cardiff Medicentre, Heath Park, Cardiff
Centre for Health Technologies Evaluation, National Institute for Health and Care Excellence, London
Cambridge University Hospitals NHS Foundation Trust, Box 218, Radiology, Addenbrooke's Hospital, Cambridge
The Christie NHS Foundation Trust, Department of Radiology, The Christie NHS Foundation Trust, Manchester
The Newcastle upon Tyne Hospitals NHS Foundation Trust, Liver Unit, Freeman Hospital, Newcastle upon Tyne
NHS England, Institute of Oncology, St James's University Hospital, LEEDS
The Christie NHS Foundation Trust, The Christie, Withington, Manchester
NIHR University College London Hospitals Biomedical Research Centre, UCL Cancer Institute, University College of London, London

Accreditation Statement
This activity has been planned and implemented in accordance with the Essentials and Standards of the Accreditation Council for Continuing Medical Education (ACCME).

The Society of Interventional Radiology (SIR) is accredited by the ACCME to provide continuing medical education for physicians. SIR designates this education activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

This program is approved for 1 self-assessment CME credit (SA-CME) by the Society of Interventional Radiology (SIR) - approved July 1, 2019. SIR is awarded Deemed Status by the American Board of Radiology (ABR). The SA-CME credit offered for this enduring activity meets the ABR’s criteria for self-assessment toward the purpose of fulfilling requirements in the ABR Maintenance of Certification (MOC) Program.